I had a lease once, for my VW. It almost turned out. I drove it for four years, but at the end of the lease I still owed more than it was worth, so I just turned it in. No problem. I had to pay the last month's lease + about 250 in damage (from a busted front spoiler). I took care of the car, so I didn't have any real issues.
Right now, I really prefer to own. My Honda is paid for, and I intend to drive it into the ground. I think owning is best generally, but it definitely depends on your financial situation. When I leased, I absolutely could not afford the extra money to buy it.